Zeitschrift für medizinische und chirurgische Pathologie
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Cellular Angiofibroma in the Space of Retzius: a Case Report

Nina K Ayala, Kerry E Drury, Kruti P Maniar and Magdy P Milad

Background: Cellular Angiofibroma (CA) is an uncommon benign tumor that generally occurs in the vulvovaginal region in women. Extra-vulvar cases have previously been described but are exceptionally rare.
Case: A 45-year-old female with an incidentally noted pelvic mass in the Space of Retzius that was presumed to be a fibroid. Excision was complicated by significant haemorrhage from the surgical bed.
Conclusion: Extra-vulvar cases of CA are rare and have never been described in the Space of Retzius. We also discuss preoperative MRI findings to aid in diagnosis and surgical planning. Additionally, this CA was highlyvascularized, resulting in massive haemorrhage after removal. This is the first case to identify haemorrhage as a source of morbidity in CA.