Pankreaserkrankungen und Therapie
Offener Zugang

Abstrakt

Cystic Fibrosis-Associated Pancreatic Dysfunction: An Elucidative Exploration

Marion Rowland

Pancreatic Cystic Fibrosis (PCF) is a significant manifestation of Cystic Fibrosis (CF), a hereditary disorder affecting multiple organ systems. Cystic fibrosis is an autosomal recessive genetic disorder caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene, located on chromosome 7. These mutations impair the function of CFTR protein, leading to abnormal ion transport across epithelial cells and subsequent dysfunction of exocrine glands, including those in the pancreas.