Andrologie- Offener Zugang
Offener Zugang

Abstrakt

Persistent Mullerian Duct Syndrome: A Challenge as Great as it is Rare

Gabriel Gomes Vieira Ribeiro Leite*

Persistent Mullerian Duct Syndrome (PMDS) is a rare condition characterized by the persistence of mullerian duct structures in genotypic and phenotypic males. Despite its rarity, PMDS poses significant diagnostic and management challenges. This commentary draws insights from the diagnosis and treatment management from the experience in treating a 37-year-old patient with PMDS in Brazil. PMDS arises from defects in Mullerian Inhibiting Factor (MIF) or its type II receptor (AMHR2), leading to the development of female reproductive structures in male individuals. Clinical presentation varies, with adults often presenting with infertility complaints or incidental findings on imaging studies.