Zeitschrift für klinische und experimentelle Dermatologieforschung
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Solitary Benign Cephalic Histiocytosis in a Taiwanese Infant

Wei-Chen Fang, Sheng-Hong Tseng, Chia-Chee Weng and Yun Chen

Benign cephalic histiocytosis (BCH) is a rare type of non-Langerhans histiocytosis with features of many small yellow, yellow-red, or yellow-brown papules located on face, head, neck, and shoulders of infants and young children. There would be no associated symptoms. The histopathological images reveal infiltration of histiocytes in dermis; immunohistochemically, the histiocytes are positive for CD68 stain, but negative for S-100 and CD-1a stain. The BCH would regress spontaneously with time, and thus no treatment is needed. However, in some cases, there would be some pigmentation or atropic scar remained. This is such a rare disease, and thus there is no case of BCH been reported in Taiwan. We recently have a chance to observe an 11-year-old boy with a solitary papule of BCH on his right scalp.