Zeitschrift für klinische Toxikologie
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A Case of Chlorfenapyr Intoxication with Central Nervous System Involvement

Ji Sun Kwon, Hye Yun Kim, Hyun Jeong Han, Je Young Kim and Jong Ho Park

Background: Chlorfenapyr is a widely used insecticide worldwide for farming. However, chlorfenapyr intoxication with organic brain lesion has never been reported.

Case report: A 49-year-old man attempted suicide by ingesting 200 ml of Chlorfenapyr. He suffered from severe diaphoresis with a sustained high fever. Ten days after chlorfenapyr poisoning, he developed altered mentality. Brain Magnetic resonance imaging (MRI) showed extensive bilateral involvement of the white matter.

Conclusion: We presumed Chlorfenapyr or its metabolite can induced delayed neurotoxicity in the central nervous system. We report herein a case of Chlorfenapyr intoxication with brain MRI findings.