Zeitschrift für klinische und experimentelle Ophthalmologie
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A Study on Visual Outcome in Central Serous Chorioretinopathy (CSCR) with Different Treatment Modalities

Jayati Pandey*

Background: CSCR is a sporadic disorder of the outer blood retinal barrier, characterized by a localized detachment of sensory retina usually affecting one eye in young males. Usually, a self-limiting disease various treatment have been investigated in recent times.

Aim: To evaluate the final visual outcome, recurrence rate and possible complications in patients of CSCR treated with observation, oral Acetazolamide, oral Eplerenone and double frequency ND-YAG laser photocoagulation.

Methods and materials: A prospective interventional study was done on patients newly diagnosed with CSCR. The study comprised of 76 patients who were divided into four groups namely Group A on observation, Group B on oral Acetazolamide Group C on oral eplerenone and Group D on Nd-YAG Laser. Visual recovery, recurrence rate and possible complications of these therapies were compared.

Results: Group D patients showed fastest improvement in visual acuity at 2 weeks. At 12 weeks all groups had comparable improvement. 3 patients in group A, 1 each in group B and D and 2 in group C showed recurrence. Paraesthesia, numbness and gastric upset related to acetazolamide were noted in 5 patients of group B. 16.7% cases in group A, 10.5% in group B, 5.3% in group C and 5% in group D showed leakage on FFA after 12 weeks.

Conclusion: In acute CSCR eplerenone seems to be efficient with least side effects and early resolution. In chronic cases ND-YAG Laser seems to give better result. Early treatment should be given for better visual recovery of patients.