Zeitschrift für Tumorforschung
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Axillary Syringocystadenoma Papilliferum in an Adult Male: A Rare Case Report

Armaghan Kazeminejad, Mohammad Jafar Ghahari, Amirsaleh Abdollahi, Sobhan Mohebbi Najmabad

Syringocystadenoma Papilliferum (SCAP) has long remained an enigmatic entity within the realm of dermatology. Typically manifesting in familiar locales such as the neck, face, and scalp, SCAP has been intricately woven into the medical consciousness as a rare and benign hamartoma. However, our case report introduces an exceptional narrative that challenges convention. In an unexpected departure from the norm, we present the case of a 29-year- old adult male with SCAP in the axilla—an atypical locale. Lacking the customary association with nevus sebaceous, this case defies traditional expectations. The patient's journey began with a tender, erythematous nodule, ultimately unveiling an extraordinary histopathological composition. Histological analysis revealed an intricate canvas of dilated ducts, squamous differentiation, horn cyst formation, and a chorus of lymphoplasmacytic cells. Remarkably, the protagonist remained devoid of malignant or atypical elements, reaffirming its benign nature. This atypical presentation of SCAP in an adult male highlight its exceptional nature, challenging clinical acumen and beckoning histological scrutiny. It adds a unique chapter to the world of dermatopathology, shedding light on diagnostic intricacies. As the curtain falls on this case, it contributes to the ever-evolving tapestry of understanding in the intricate world of dermatopathology, enriching the medical narrative and offering valuable insights into an enigmatic dermatological puzzle.