Zeitschrift für klinische und experimentelle Ophthalmologie
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Abstrakt

Bilateral Chronic Central Serous Chorioretinopathy (CSCR) Induced by Long-Term Testosterone Treatment

Hsin-Ying Lin and Kai-Ling Peng

Purpose: We reported a rare case of bilateral chronic central serous chorioretinopathy (CSCR) induced by long-term exogenous testosterone treatment.
Method: A case report.
Result: A 52-year-old man with medical history of diabetes mellitus, hypertension, diabetes insipidus and hypogonadism presented to our ophthalmologic clinic with unstable blurred vision of right eye for more than 5 years and vision loss of left eye since childhood injury. Optical coherence tomography (OCT) showed subfoveal fluid in both of his eyes. Fluorescein angiography (FA) revealed fluorescein in multiple leaking points around the arcade area, which appeared hyperfluorescence not only in early phase but sustained fluorescein pooling till late phase in both eyes. According to his medical records, he received intramuscular testosterone injection every two weeks as treatment of hypogonadism for more than 10 years. His serum level of testosterone was higher than normal range. After focal photocoagulation in his right eye combined with decreasing frequency of testosterone intramuscular injection, the subfoveal fluid in both of his eyes totally resolved with vision improvement.
Conclusion: Testosterone related bilateral CSCR was rarely reported previously. It’s very important to review patients’ medical conditions and medications if there were unresolved or repeated episodes of bilateral CSCR.