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Congenital cytomegalovirus infection presenting with intrapulmonary calcifications on prenatal sonogram

Prem Fort, Millie R. Chang2, Suresh Boppana, Richard O. Davis, John Owen, Waldemar A. Carlo

Cytomegalovirus (CMV) is the most common congenital viral infection in developed countries. Although pneumonitis has been reported in infants with congenital CMV infection, involvement of the lung parenchyma is less common in congenital than in perinatal CMV infections. We report an infant with congenital cytomegalovirus (CMV) infection and multiple intrapulmonary calcifications on prenatal sonogram that had congenital pneumonia and persistent oxygen requirement after birth. To our knowledge, this is the first case report of a live-born infant with pulmonary calcifications due to CMV noted on prenatal sonograms.