Zeitschrift für klinische und experimentelle Ophthalmologie
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Corneal Structure and Disease: Correlating the Corneal Anatomy with its Clinical Pathology

Radhika Natarajan*, Nikhil Toshniwal

Disorders of the cornea can be interpreted to a large extent based on the structural uniqueness of its layers. Here, we attempt to correlate the corneal anatomy with some of its pathology. This would aid better teaching as well as understanding of common corneal diseases.

Common and unique corneal diseases affecting the corneal epithelium, Bowman’s layer, stroma, Descemet’s membrane and endothelium, seen routinely in our tertiary care corneal practice have been enlisted. Disorders altering the structural characteristics of the cornea, such as its front and back curvature, thickness, neurovascular supply etc., have also been included. The relevant anatomical characteristics of these structures have been referenced from peer-reviewed literature and standard textbooks for correlation.

An attempt has been made to correlate the disease pathology of important corneal conditions with the anatomic characteristics of its layers. Embryological and structural connotations of corneal disease were also studied. The results depict the relevant applied clinical anatomy of corneal diseases which has not been compiled before in literature.