Anatomie und Physiologie: Aktuelle Forschung
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Effects of Interdialytic Weight Gain on Lung Function Tests in Hemodialyzed Patients

Kovacevic P, Rajkovaca Z, Jakovljevic B, Kovacevic T, Momcicevic D and Veljkovic S

Complications of respiratory system in patients suffering from chronic renal failure who are treated with regular haemodialysis are well known. However, the effects of interdialytic weight gain on respiratory function in these patients are less known. Hence, this study was designed with the aim to determine the potential differences in spirometry related to the different interdialytic weight gain.

The study included 32 patients, 16 males (50%) aged 51 (± 11), with ESRD who had been treated with repeated haemodialysis. The patients were divided into two groups: Group 1 – patients with interdialytic weight gain < 5% and Group 2 – patients with interdialytic weight gain > 5%. All patients had spiromety done before (A) and after (B) haemodialysis.

The results obtained show vital capacity means (X) measured before (A) and after haemodialysis (B) in group 1: A=2.95 ± 0.9 and B=3.9 ± 1.2 and group 2: A=3.4 ± 1.1 and B=3.8 ± 1.12. Forced vital capacity means (X) measured before (A) and after haemodialysis (B) in group 1: A=2.9 ± 0.85 and B=3.2 ± 1.0 and group 2: A=3.7 ± 1.4 and B=3.8 ± 1.35. Forced expiratory volume in first second means (X) measured before (A) and after haemodialysis (B) in group 1: A=2.4 ± 0.78 and B=2.7 ± 1.1 and group 2: A=3.3 ± 1.25 and B=3.4 ± 1.33.

The results lead us to a conclusion that haemodialysis has a positive effect on pulmonary ventilating function, but this effect is smaller in patients with greater interdialytic weight gain.