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Exploring the Potential of Small Regulatory RNA towards Microbial Engineering

Singh V and Braddick D

Metabolic engineering has the potential to produce chemicals, fuels, drugs and more at industrial levels in a cost effective manner by manipulation of enzymatic, transport and regulatory function within cells. Small regulatory RNAs (sRNAs) play a key role in up and down regulation of genes associated with biosynthetic pathway for increasing production level. Therefore, sRNA is a rapid, sensitive and versatile tool for microbial engineering.