Zeitschrift für klinische und experimentelle Dermatologieforschung
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Giant Seborrheic Keratosis of the Genitalia Clinically Mimicking a Genital Wart

Alan Sevil and Cumhur Ibrahim Başsorgun

Seborrheic keratosis is one of the most prevalent benign skin tumors. It is most frequently determined in body, extremities, head and neck. Genital region located seborrheic keratosis is rarely encountered and it is frequently misdiagnosed as genital wart. HPV has been blamed in etiology. Genital HPV positivity at varying rates in genital and extra-genital located SK’s has been reported. In this study, we reported a 35 year-old male case applied to the hospital with common verrucous masses in external genital region. Dermoscopic examination showed fissures and ridges, cerebriform appearance comedo-like openings, consistent with SK. The histopathology confirmed the diagnosis of SK. In histopathologic examination, the acanthosis that include basaloid cell proliferation consisting of thick keratohyalin granules and a keratinized plug structures drew attention on analysis of the sections. HPV was determined on biopsy material through the PCR method. HPV6 and HPV16, HPV6 as the dominant, were determined in performed HPV typing. In our case, HPV growth is a finding supporting the role of HPV in etiology.