Zeitschrift für pharmazeutische Pflege und Gesundheitssysteme
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Improvement of Solubility and Dissolution by Liquisolid Compact

S.V Phoke, A.D Hatkar, S.S Jaybhaye

Liquisolid technique is a new technique for the drugs which has solubility problem. This technique proved to increase dissolution of poor water soluble drugs. In this technique liquid medications such as solutions or suspensions of water insoluble drugs in suitable non-volatile liquid vehicles can be changed into suitably flowing and compressible powders via blending with elected powder excipients. In these drug is held in solution around and excipient powder in surrounding, so drug is present in solubilized form, which increase dissolution.