Zeitschrift für klinische und experimentelle Ophthalmologie
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Abstrakt

Investigating the Impact of Endogenous Testosterone Levels on Central Serous Chorioretinopathy

Radhika Gupta, Raji Kurumkatti, HS Trehan, Tanmay Mohapatra, PK Singh, Yogesh Yadav

Aim: This study aimed to explore the potential involvement of endogenous testosterone levels in the etiopathogenesis of Central Serous Chorioretinopathy (CSCR).

Materials and methods: Conducted as a case-control study with 82 participants selected from a tertiary care center in North India, the subjects were categorized into 41 cases and 41 controls. Fasting blood samples were collected in the early morning to assess serum testosterone levels, measured using the chemiluminescent immunoassay method.

Results: The mean age for CSCR patients and controls was 35.71 ± 5.82 years (range 22-49 years) and 33.71 ± 8.42 years (range 20-50 years), respectively. The median serum testosterone level in cases was 4.79 ng/ml, with an odds ratio of 3.16. However, the 95% Confidence Interval (CI) of the odds ratio, ranging from 0.31 to 31.7, indicated no significant association between endogenous testosterone levels and central serous chorioretinopathy.

Conclusion: This study concludes that there is no statistically significant correlation between Central Serous Chorioretinopathy (CSCR) and elevated endogenous serum testosterone levels.