ISSN: 2161-0932
Sreejith Kodakkattil
Hereditary angiooedema (HAE) is characterised by recurrence of cutaneous and mucous membrane swellings in any part of the body. Symptoms usually appear early in life and are normally accompanied by a family history because the disease is inherited in an autosomal dominant manner. The spontaneous mutation rate is about 25% and more than 1001 inhibitor gene mutations have been described′different C1 inhibitor gene mutations have been described.