Zeitschrift für Umweltverschmutzungseffekte und -kontrolle
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Abstrakt

Manganese Exposure and Toxicity

Seyedtaghi Mirmohammadi

One of the main essential elements for human is Manganese (Mn). Furthermore Mn is a row material for many king of ferrous foundry and there is a working exposure to Mn for workers in the workplaces. High exposure to Mn can result in increase in human tissues levels and neurological effects. Though, there should be some threshold limit value for Mn exposure related to adverse effects may occur and increase with higher exposures further than threshold limit. Conclusions from scientific literatures related to Mn toxicity revealed that this pollutant can effect on brain system and create some neurological disorders or neurological endpoints which measured in many of the occupational health assessments. Many researches have tried to show a relationship regards to biomarkers with neurological effects, such as neurological changes or magnetic resonance imaging (MRI) changes have not been founded for Mn. More precise study need for Mn risk assessment for industrial pollution exposure and it will be used to recognize situations that may guide to understand Mn accumulation on brain and Mn metabolism in different exposed workers. Workplace evaluations for Mn will prepare valuable scientific information for the development of more scientifically sophisticated guidelines, regulations and recommendations for future study and for Mn occupational toxicity control and exposure prevention in the related workplaces.