Klinische und experimentelle Kardiologie
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Abstrakt

Microparticles in Atherosclerosis: Biomarkers of Disease

Kunal Mahajan

Microparticles (MPs) are membrane vesicles released by various cell types (platelets, endothelial cells, monocytes) in circulation, which play inevitable role in thrombosis and vascular inflammation. Literatures so far suggested MPs as biomarkers of vascular injury and inflammation and also contribute to the initiation and development of atherosclerosis and its related manifestations. Atherosclerosis is the major underlying pathophysiology for the various cardio vascular diseases (CVDs). In addition, most recent data suggest a potential prognostic role of circulating MPs. Present article summarizes briefly about the different MPs and their importance as markers to check the vascular health in various CVDs.