Zeitschrift für Nanomedizin und biotherapeutische Entdeckung
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Nanofibrous Structure of Chitosan for Biomedical Applications

Christopher Mahoney, Matthew B. Mccullough, Jagannathan Sankar and Narayan Bhattarai

Over the past decade, there has been a strong growing interest in using several forms of chitosan, more specifically nanofibers, for various biomedical applications. Chitosan has several impressive biological characteristics including but are not limited to its great biocompatibility and biodegradability, anti-bacterial properties, and cytocompatibility. In order to create nanofibers from this natural polymer, the electrospinning has been widely used as the most effective technique to produce a stable structure. Overtime, a number of challenges have been overcome through the development of mechanically and structurally intact, biocompatible and multi-functional nanofibers. The recent progress of the nanofibrous structure of chitosan and their biomedical applications in tissue engineering, drug delivery, wound dressing, and antimicrobial are discussed.