Zeitschrift für Frauengesundheit
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O-Shot: Platelets Rich Plasma in Intimate Female Treatment

Neto JB*

Background and objectives: This pilot study measures the response of women with stress incontinence, overactive bladder, lubrication and sexual dysfunction (libido, arousal, dyspareunia) to evaluate the safety, tolerability and clinical efficacy of “O-Shot” Platelets Rich Plasma (PRP) of the vulvo vaginal field. PRP has recently been shown to accelerate rejuvenate aging skin by various growth factors and cell molecular adhesions. Each patient received two sessions at the intervals of two months apart.
Material and methods: This is a first prospective study in Brazil, in a private clinic, non-randomized controlled, in non-selected 68 women performed by the same doctor (author) between August 1st 2016 to February 1st 2017. All Patients were fully informed of the therapeutic innovation of the PRP injection (O-Shot) and consented to the procedure. Sixty-eight women, non-select ages of 32-97 (average: 62.8 years old) were included in this pilot study and self-reported having stress incontinence (13 patients), overactive bladder (15 patients), mixed (22 patients), lack of lubrication and sexual dysfunction (libido, arousal, dyspareunia). Detailed history, physical examination, questionnaire, neurological tests, urine sample, Q-tip test and stress test were performed. All patients were followed by the author each two weeks until the end of protocol. The protocol was based on two sessions of Platelet Rich Plasma (O-Shot) two months apart, no matter if the patient was satisfied or not with the first session.
Results: About sixty-eight women in the age ranging from 32 to 97 (average: 62.8 years old) were enrolled in this study. Of the sixty-eight patients, 94% of them were satisfied, only 6% of them with overactive bladder did not have any improvement with this treatment.
Conclusion: Platelet Rich Plasma, “O-Shot” is an in-office treatment that is safe, effective, non-surgical, and nonhormonal option for women having stress incontinence, overactive bladder, lack of lubrication, and sexual dysfunction, such as lack of libido, arousal or dyspareunia.