Zeitschrift für klinische und experimentelle Dermatologieforschung
Offener Zugang

Abstrakt

Prospective Randomized, Double-Blind Study to Evaluate Dietary Supplements for Impacts on Skin Appearance in Healthy Women

Paula Simpson, Rodney Benjamin*

Objective: Data suggests both Methylsulfonylmethane (MSM) and high dosage Hydrolized Fish Collagen (HFC) independently support skin health and reduce visible signs of aging. The goal of this study was to determine if MSM combined with HFC has benefits for skin health and if the combination acts synergistically to facilitate lower dosages of HFC and provide superior results to MSM alone.

Design and patients: A total of 58 females aged 41-65 participated in this double-blind placebo controlled study. They were randomly assigned to one of three groups; placebo, 1000 mg of MSM/day or combo 1000 mg+2500 mg of HFC/day. Efficacy was determined using instrumentation, expert (dermatologist) evaluation and subject selfassessment.

Results: Instrumental analysis showed near equal improvement in wrinkle reduction by Clarity Pro-3d evaluation by both the MSM and combination groups from baseline however, statistically significant improvement in elasticity as measured by cutometer (p=0.0097) was reached only in the combination group.

Conclusion: While both MSM and HFC reduce visible signs of aging, the combination of these two ingredients support lower dosing of HFC and may provide superior results to MSM alone.