Zeitschrift für klinische und zelluläre Immunologie
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Recent Advances in Immunology

Abdhul Rehman Asif

Van Wyk Grumbach syndrome (VWG) is a rare syndrome characterized by precocious puberty, hypothyroidism, delayed skeletal maturation and bilateral ovarian cysts. Majority of these features are with thyroxine supplementation including ovarian cyst. This case report illustrates a case of 6 yr old girl who presented with vaginal bleeding and pain abdomen. She had hypothyroidism. The ultrasound abdomen reported multicystic ovarian cysts in bilateral ovaries. Timely done thyroid function tests and prompt diagnosis of VWG syndrome alleviated the need of a major surgery.