Zeitschrift für Angewandte Pharmazie
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RISK FACTORS LEADING TO HIGH PREVALENCE OF BREAST CANCER

Rabia Tariq, Sadia Huma, Marriam Zaka Butt, Fatima Amin

Breast cancer in women causes psychological and physical distress. It is the most commonly diagnosed female cancer in all cancers. Breast cancer is among the top 20 causes of deaths in Pakistan. It is believed that various factors such as gender, age, socioeconomic status, family history, physical activity, smoking, breastfeeding/lactation, no. of full term and incomplete pregnancies, hormonal and reproductive factors influence the incidence of breast cancer. A prospective as well as retrospective study was conducted on 100 patients in different hospitals of Lahore, aiming to evaluate risk factors leading to high prevalence of breast cancer in women. A questionnaire was designed to obtain patient history, patient complaint and management regarding disease. Females of all age groups were included in the study. The data collected was analyzed and presented in the form of graphs and tables. The results were derived and conclusion presented. Women with advanced age, having middle class family background, higher body mass index and a high ratio of incomplete pregnancies were at significantly increased risk of breast cancer. Obesity and the use of oral contraceptives are minor whereas family history, employment status, physical activity and smoking don’t serve as risk factors. The protective role of breastfeeding/lactation and full term pregnancies is suppressed and not very significant.