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Tacrolimus Therapy in Optimizing Immunosuppression for Transplant Patients

Irena Katherine

Tacrolimus, a potent immunosuppressive medication, has revolutionized the field of organ transplantation by significantly improving graft survival rates and reducing the risk of rejection. As a calcineurin inhibitor, tacrolimus exerts its immunosuppressive effects by inhibiting the activation of T-lymphocytes, thereby preventing the immune system from mounting an attack against the transplanted organ. In optimizing immunosuppression for transplant patients, tacrolimus therapy plays a central role in achieving the delicate balance between preventing rejection and minimizing the risk of adverse effects.