Klinische und experimentelle Kardiologie
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To Follow up Of Patients with Coronary Artery Disease with Severe Left Ventricular Systolic Dysfunction: Novel Approach

Sharad Masudi, Anugrah Nair, Saritha Shekar

Coronary artery disease (CAD) associated with left ventricular systolic dysfunction is a condition related to poor prognosis. There is a lack of robust evidence in many aspects related to this condition, from definition to treatment. Significant left ventricular systolic dysfunction is defined as an LVEF less than 40%. There is no simple measure of diastolic function. CHF due to diastolic dysfunction may be so common in the elderly because aging itself results in a stiff, poorly relaxing left ventricle. Disease processes add to these aging effects. If you have systolic heart failure, you can have: Shortness of breath. Tiredness, weakness, swelling in feet, ankles, legs, or abdomen, common prescriptions for left ventricular dysfunction are: Diuretics or water pills: Treats swelling of feet and abdomen. Beta-blockers: Slows heart rate and regulates blood pressure. ACE inhibitors, ARB, ARNI: Widen blood vessels. LV systolic dysfunction was defined as an ejection fraction (EF) of less than 40% by echocardiography. The recovery of LV systolic function was defined as recovery of the EF to a level of 40% or greater and a net increase in EF of 10% or greater. In this research paper we are executing statistical analysis, observation and method along with result analysis. Sources of Data: This review is based on the published academic articles as well as our clinical experience. Background: Background and aim: The choice of optimal treatment strategy in patients with coronary artery disease (CAD) and severe left ventricular (LV) dysfunction is often difficult. The aim of this study was to compare long-term results of patients with chronic CAD, severe heart failure and a defined scope of myocardial viability treated with coronary revascularization, heart transplantation, or kept on medical therapy. Materials And Methods: Sequential randomized sampling of patients who meet the inclusion criteria from 2015-18 & who were on regular follow up for at least 2 yrs. were included in the study Result: There was a trend towards improvement in LV systolic function among patients who underwent revascularization (PTCA & CABG) as compared to medical management, though it was not statistically significant. The patients with CAD with LV dysfunction who received ARNI showed reduction in heart failure repeat hospitalizations. This was seen in patients, irrespective of the management strategy.