Zeitschrift für klinische und experimentelle Ophthalmologie
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Visual Disorders in Optic Neuromyelitis: Report of Two Cases

Yaimara Hernández, Yannara Columbié, Odelaysis Hernández, Jose A. Cabrera and María A. Robinson

Optic neuromyelitis is a disease caused by autoimmune disruption of the aquaporin 4 channels of central nervous system, whose involvement is more frequent over the spinal cord and optic nerves as well as in specific areas of the brain. Optic neuritis in optic neuromyelitis can occur simultaneously with transverse myelitis or separated by a variable time interval of days or even years. It may be unilateral or bilateral and could occur in recurrent forms. We describe a 35-year-old woman with visual loss due to acute bilateral optic neuritis and a 46-year-old woman with unilateral optic neuritis that were admitted at the neuro- ophthalmology service of the Cuban Ophthalmology Institute last year. Both were treated with intravenous methylprednisole for five days. Three month later neurologic symptoms appeared, a magnetic resonance imaging was performed and the optic neuromyelitis diagnosis was confirmed. We show the results of the neuro-ophthalmology studies before and three month after the treatment.