Zeitschrift für klinische und experimentelle Dermatologieforschung
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A Diffuse Bullous Cutaneous Mastocytosis Mimicking a Bullous Toxidermia in a Black Child

Dégboé Bérénice, Koudoukpo Christiane, Kouassi Alida, Agbéssi Nadège, Gaulier Alain, Akpadjan Fabrice, Mensah Prisca, Ngolo Pascaline, Adégbidi Hugues and Atadokpèdé Félix

We report a 16-month-old black girl received at emergency with a history of generalized and itchy bullous and post-bullous eruption occurred 24 hours after administrating ibuprofen for acute otitis. The diagnosis of bullous toxidermia was retained and the evolution was quickly favorable. She was seen seventy-two hours after leaving hospital for pruritic papulo-vesiculo-bullae located on the head, face, necklines, buttocks, perineum and legs after eating crustacean on the day before. The biopsy of a papulo-bullae lesion led to (after the different stains (hematoxylin, Giemsa, toluidine blue) corroborating with immunohistochemical typing with anti CD117) the diagnosis of bullous cutaneous mastocytosis.