Zeitschrift für medizinische Diagnosemethoden
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A Man with Breast Cancer Following Hormonal Treatment for Prostate Cancer

NG Cathy Po Ching, TSUI David Ka Kin, YAU Kevin Kwok Kay and TANG Chung Ngai

Male breast cancer is rare with an annual incidence of less than 1% in Hong Kong. Some postulate the effect of estrogen as an important risk factor for development of male breast cancer. With the increasing use of hormonal therapy for patients with prostatic cancer, it may result in hormonal imbalance with a relative hyper-estrogenic state, which may increase the risk of male breast cancer. However so far there is no clinical evidence of its causal effects. Here we report a case of development of breast cancer in male patient after hormonal treatment (luteinizing hormone releasing hormone analog and anti-androgen) for prostatic cancer, and followed by a review of the literature for the association between them.