Gynäkologie und Geburtshilfe
Offener Zugang

Abstrakt

Management of Patients with Pregnancy-Associated Ovarian Clear Cell Carcinoma: A Mini-Review

Takehiro Serikawa, Koichi Takakuwa and Takayuki Enomoto

A 39-years-old pregnant woman in the 9^th week of gestation was referred to hospital for an ovarian mass of 5 cm in diameter. The size did not increase during the pregnancy and a female infant was delivered at term. Nine months after delivery, the solid part of the mass grew and clear cell borderline tumor was suspected by MRI. A laparotomy was performed, the pathological diagnosis was a Clear Cell Carcinoma (CCC), and FIGO stage was stage Ia. The patient remains free of disease at 6 months after the operation. The incidence of ovarian cancer diagnosed during pregnancy is very low and CCC is rare, so that there are very few reports of pregnancy-associated CCC. We reviewed the existing literature, using the key words “ovarian clear cell carcinoma” and “pregnancy”. Besides our case, we were able to accumulate 8 cases. Their mean age is 34 years old. Eight of the 9 patients were asymptomatic at diagnosis. The size of cyst was larger than 6 cm, except for our case. All 9 patients underwent surgery and the tumors were all resectable. The FIGO stage was stage I or II. Fortunately, all patients and live-born infants were alive and well.