Zeitschrift für genetische Syndrome und Gentherapie
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Mitochondrial Eve: Its Genetic Implications

P D Gupta

Mitochondria are an essential cell organelle for all living cells, if they are eliminated from the cell that means the cell has undergone terminal differentiation. It works like sub-kingdom in the cell; in addition to provide energy to the cell it has its own gasket of synthetic machinery. In each individual it is contributed by mother. If there is any defect (mitochondrial DNA mutation) in this organelle whole body suffers in a variety of ways. Recent researches are contributed towards corrections of mitochondrial defects by mitochondrial replacement or by infusion of healthy mitochondria.