Zeitschrift für Nanomedizin und biotherapeutische Entdeckung
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Nanomedicine & Drug Delivery: Dendrimer nanotechnology for biomedical applications

Ling Peng

Nanotechnology is widely expected to bring breakthroughs in specific delivery of the right therapeutic agent to the right patient at the right disease lesion. Dendrimers are ideal nanocarriers for drug delivery by their uniquely well-defined structures and multivalent cooperativity confined within a nano-sized volume per Se. We have established bio-inspired structurally flexible and self-assembling supramolecular dendrimers for drug delivery. These dendrimers are excellent nanocarriers for personalized medicine: They can form modular, responsive and adaptive nanosystems and effectively deliver various chemo and bio-therapeutics as well as imaging agents for precise diagnosis and personalized treatment in various diseases’ models. These studies have offered new perspectives in dendrimer nanotechnology based biomedical applications.