Zeitschrift für Krebswissenschaft und -forschung
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Abstrakt

Role of NSAIDs in Cancer Prevention and Cancer Promotion

Vaibhav Walia, Shabnam Thakur*

The malignancy state is studied with the help of inflammatory reaction of non-steroidal anti-inflammatory drugs and its prevention is studied. The Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) are usually given by physicians in many clinical conditions for the symptomatic treatment of pain and fever. They have anti-inflammatory properties, and these drugs have been investigated for their anticancer effects in various studies. This is because chronic inflammation has a wide connection to carcinogenesis. Anti-inflammatory drugs are also used in cancer treatment and prevention. In the past few years, research has been made that NSAIDs may lower the risk of certain types of cancer. However, there is also research that proves the contrary. NSAIDs are also known for many side effects, including some life-threatening ones.

The use of NSAIDs which includes the risk of gastric cancer and aspirin has a relation between themselves which has not been well studied. This review has been performed in a systematic way and used the analysis of published information to know the association between use of this class of drugs and the risk of gastric cancer. This review will give the relation between the role of NSAIDs in cancer prevention and cancer promotion and chronic inflammation.