Innere Medizin: Offener Zugang
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Abstrakt

Prevalence of Antibiotic-Resistant E.coli Causing Urinary Tract Infection in Jinnah Medical College Hospital

Shazli Razi, Zulqurnain Younas

Objective: To determine the prevalence of E.coli causing Urinary Tract Infection (UTI) in JMCH during one year 2020-2021. To determine the resistance and sensitive drugs acting on E.coli.

Background: Most frequently, Urinary Tract Infection (UTI) infection is caused by E.coli, requiring urgent medical attention. Normally E.coli lives abundantly in rectum but when this bacterium comes in urethra it can cause UTI’s.

Methods: The retrospective study included 538 patients of which 261 were males and 275 females were admitted to Jinnah Medical College Hospital, Karachi between February 2, 2020-January 20, 2021. The ages, gender, presence of E.coli along with sensitivity and resistance against drugs were recorded and analyzed using SPSS version 16.

Results: Of the 538 patients, 261 (48.5%) were males and 275 (51.1 %) were females. The age range was from 1-100 years with mean age between 40.07 years and mean SD ± 20.105. The female to male ratio was 0.95. Of the 538 patients, 102 were infected with E.coli. The most sensitive antibiotics against E.coli was Imipenem (87 patients), Fosphomycin (80 patients) nitroflurantoin (59 patients), Tazobactam (56 patients). The most resistant antibiotic against E.coli were amoxacillin+clavulinic Acid (83 patients), Septran (75 patients), Cefuroxime (72 patients), Ceftriaxone (59 patients). Prevalence of E.Coli during 1 year was 18.9%.

Conclusion: E.coli infection is high in females in the study region. E.coli is most sensitive to Imipenem and most resistant to amoxacillin+clavulinic Acid. UTI can be prevented by good personal hygiene and drinking plenty of water. UTI’s are easy to treat if proper diagnosis is made.