Zeitschrift für klinische und experimentelle Dermatologieforschung
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Langerhans Cell Histiocytosis in Postmenopausal Female with Intractable Pruritus: A Rare Case Report

Navya Handa, Pankaj Rao, Dilip Kachhawa, Rohitashva Dana and Vinod Jain

Langerhans cell histiocytosis (LCH), characterised by the infiltration of one or more organs by large mononuclear cells, may affect patients of any age but in adults the features of this disease is still poorly defined. Here, we report a case of an adult with crusted erosions in seborrheic distribution, Bilateral inguinal lymphadenopathy with ulceration, which on biopsy showed features of multisystem LCH, and was confirmed by immunohistochemistry. Despite chemotherapy and high dose antihistamines our patient complained of intractable pruritus which was relieved with Narrow Band UV-B phototherapy.