Journal of Theoretical & Computational Science

Journal of Theoretical & Computational Science
Offener Zugang

ISSN: 2376-130X

Abstrakt

Green Synthesis of Tetrazines and their Role as Human Cytomegalovirus (HCMV) Protease Inhibitor

Singh P and Kumari K

Herein, we report a one-pot, efficient, and environmentally benign synthesis of biological and pharmacological potent tetrazines and tetrazines were synthesized via reaction of benzyl cyanide and hydrazine in the presence of sodium nitrite and hydrochrloic acid at room temperature in bronsted acidic ionic liquid as a green solvent and efficient catalytic media. Further, computational studies of the synthesized tetrazines have been performed against Human cytomegalovirus (HCMV) protease and found to inhibitors for HCMV. Therefore, tetrazines have been proposed as potent antiviral agents.

Haftungsausschluss: Diese Zusammenfassung wurde mithilfe von Tools der künstlichen Intelligenz übersetzt und wurde noch nicht überprüft oder verifiziert.
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